Best Medicine is a medical comedy-drama series developed by Liz Tuccillo. Based on the British series titled Doc Martin by Dominic Minghella, the Fox series follows Dr Martin Best, a brilliant but grumpy surgeon who develops a fear of blood, which prevents him from continuing to work as a surgeon. He decides to move from Chicago to the sleepy town of Port Wenn, but soon clashes with the locals who don’t know his secret. Best Medicine stars Josh Charles, Abigail Spencer, Josh Segarra, Cree, and Annie Potts. So, if you loved the feel-good story, hilarious comedy, and likeable characters in Best Medicine, here are some similar shows you should check out next.
Doc Martin (Acorn TV, Pluto TV, Tubi, The Roku Channel, & Rent on Prime Video)

Doc Martin is a British medical comedy-drama series created by Dominic Minghella. The ITV series follows surgeon Martin Ellingham, who develops haemophobia and reluctantly moves from London to the small village of Portwenn. He soon begins a clash with the locals, but things change when he becomes accustomed to the slow pace of living. Doc Martin stars Martin Clunes, Caroline Catz, Ian McNeice, Joe Absolom, John Marquez, Selina Cadell, and Jessica Ransom.
Everwood (Prime Video)

Everwood is a drama series created by Greg Berlanti. The WB series revolves around New Yorker Dr Andrew Brown and his two children, who move to the small town of Everwood after his wife dies, but they struggle to fit in with the local community. Everwood stars Treat Williams, Gregory Smith, Emily VanCamp, Debra Mooney, John Beasley, Vivien Cardone, Chris Pratt, and Stephanie Niznik.
Northern Exposure (Rent on Prime Video)

Northern Exposure is a comedy-drama series co-created by Joshua Brand and John Falsey. The CBS series follows Dr Joel Fleischman, who reluctantly moves to Alaska to practice medicine so that his massive medical school tuition could be paid by the government. Northern Exposure stars Rob Morrow, Barry Corbin, Janine Turner, John Cullum, Darren E. Burrows, John Corbett, and Cynthia Geary.
Hart of Dixie (Prime Video)

Hart of Dixie is a comedy-drama series created by Leila Gerstein. The CW series follows New Yorker Dr Zoe Hart, whose dreams of becoming a heart surgeon are crushed after an unfortunate incident, and she reluctantly accepts an offer to work as a general practitioner in the small town of Bluebell, but soon finds herself clashing with the locals. Hart of Dixie stars Rachel Bilson, Jaime King, Cress Williams, Wilson Bethel, Scott Porter, Tom Matheson, and Kaitlyn Black.
Hometown Cha-Cha-Cha (Netflix)

Hometown Cha-Cha-Cha is a South Korean romantic comedy-drama series developed by Kim Je-hyeon. Based on the 2004 South Korean film Mr Handy, Mr Hong, the TVN series follows Yoon Hye-jin, a successful dentist from the city who decides to move to a seaside village on a whim but struggles to blend in with the locals and is helped by a peculiar handyman loved by the entire community. Hometown Cha-Cha-Cha stars Shin Min-a, Kim Seon-ho, and Lee Sang-yi.
All Creatures Great and Small (PBS & Rent on Prime Video)

All Creatures Great and Small is a British comedy-drama series created by Ben Vanstone. Based on James Herriot’s book series If Only They Could Talk, the Channel 5 series is set in the 1930s in Northern England, and it follows rookie veterinarian James Herriot as he arrives in the Yorkshire Dales to start a job with the brilliant but eccentric veterinarian Siegrfried Farnon and soon falls in love with small-town living. All Creatures Great and Small stars Samuel West, Anna Madeley, Nicholas Ralph, Callum Woodhouse, and Rachel Shenton.
Virgin River (Netflix)

Virgin River is a romantic drama series created by Sue Tenney. Based on Robyn Carr’s novel series of the same name, the Netflix series follows Melinda “Mel” Monroe, a nurse practitioner looking for a fresh start as she takes up a job in a small North California town, but her new small town life is not exactly what she expected it to be. Virgin River stars Alexandra Breckenridge, Martin Henderson, Colin Lawrence, Jenny Cooper, Lauren Hammersley, and Annette O’Toole.
Once Upon a Small Town (Netflix)

Once Upon a Small Town is a South Korean romantic comedy series written by Baek Eun-kyeong. Based on Park Ha-min’s web novel Accidental Country Diary, the Netflix series follows Han Ji-yul, a veterinarian from the city who reluctantly begins working in a small village to take care of his grandfather’s clinic while he is away. Things change when he meets the local police officer and begins to enjoy the slow pace of life. Once Upon a Small Town stars Park Soo-young, Choo Young-woo, Baek Sung-chul, and Jung Suk-yong.
Royal Pains (Rent on Prime Video)

Royal Pains is a medical comedy-drama series co-created by Andrew Lenchewski and John P. Rogers. The USA Network series follows Hank, a brilliant doctor who’s been ousted from his job after an unfortunate incident, and reluctantly moves to the Hamptons and becomes a doctor-for-hire for the rich. Royal Pains stars Mark Feuerstein, Paulo Costanzo, Reshma Shetty, Brooke D’Orsay, Ben Shenkman, Jill Flint, and Campbell Scott.
Dr. Romantic (Netflix, Hulu, Disney+, Kocowa, & Rakuten Viki)

Dr Romantic is a South Korean medical drama series written by Kang Eun-kyung. The SBS TV series revolves around Kim Sa Bu, a brilliant and successful surgeon who mysteriously leaves his job at a big hospital and disappears. It is soon revealed that he started working at a rundown hospital in a small town as he takes in two trainees. Dr Romantic stars Han Suk-kyu, Yoo Yeon-seok, Seo Hyun-jin, Ahn Hyo-seop, Lee Sung-Kyung, and Kim Joo-hun.
